This defect happens, well regularly.
I will be jamming or listening to some music cause I do like to use my line 6 to plug up to some speakers, and just jam to songs.
Now, once in a while it will basicly "shut down" the led lights for the clip dont flash and the meters still glow but do not recognize input sound.
So once i unplug it from my pc and plug it back in the clip lights flash back and forth.
Once this happens any other usb device such as a mouse etc will shut down as well.
so im wondering is it the drivers? because it says its all updated and im not sure its really annoying.